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(May 2001)

As the body works to support a growing life, oxygen consumption increases, and the placentaa temporary organfunctions at a very high rate

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While proteostasis is governed by a network that collectively controls the biogenesis, folding, trafficking, and degradation of proteins present within and outside the cell, metallostasis is likewise controlled by a network of metal sensing, transport, speciation and ultimately trafficking of these finite inorganic resources to a specific task (Figure 1)